5.0 Critical Care

     A: Definition of sepsis: documented or presumed infection and 2 or more of the following clinical variables.
  1. Documented or presumed infection
    • Confirmed or clinically suspected pathologic process induced by microorganisms
    • Pathologic or radiographic confirmation not required to begin therapy if bedside clinical suspicion is high
  2. General inflammatory variables
  3. Tissue-perfusion variables
  4. Mild organ dysfunction Support clinical suspicion of sepsis

Tiffany M. Osborn, H. Bryant Nguyen and Emanuel P. Rivers. Emergency Medicine and the Surviving Sepsis Campaign: An International Approach to Managing Severe Sepsis and Septic Shock. Annals of Emergency Medicine, Volume 46, Issue 3, September 2005, Pages 228-231.

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